2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. MCHR1 (GPR24)
  5. MCHR1 (GPR24) Inhibitor

MCHR1 (GPR24) Inhibitor

MCHR1 (GPR24) Inhibitors (4):

Cat. No. Product Name Effect Purity
  • HY-107625A
    SNAP 94847 hydrochloride
    		Inhibitor 99.90%
    SNAP 94847 hydrochloride is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. SNAP 94847 hydrochloride binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters.
  • HY-N2073
    Ethyl linolenate
    		Inhibitor ≥98.0%
    Ethyl linolenate is a fatty acid ethyl ester (FAEE). Ethyl linolenate plays an active role in inhibition of the cellular production on melanin with an IC50 of 70 μM. Anti-melanogenesis Effects.
  • HY-120608
    BMS-814580
    		Inhibitor
    BMS-814580 is an orally active, highly efficacious MCHR1 inhibitor with a Ki of 16.9 nM against hMCHR1. BMS-814580 shows antiobesity activities.
  • HY-N2073S
    Ethyl linolenate-d5
    		Inhibitor
    Ethyl linolenate-d5 is the deuterium labeled Ethyl linolenate. Ethyl linolenate is a fatty acid ethyl ester (FAEE). Ethyl linolenate plays an active role in inhibition of the cellular production on melanin with an IC50 of 70 μM. Anti-melanogenesis Effects[1].